ischemic brain injury — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1856	Colivelin		Beta Amyloid , STAT
	Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).		Beta Amyloid , STAT
T6595	Moexipril hydrochloride	Moexipril HCl,RS-10085,SPM 925,CI-925	Apoptosis , RAAS
	Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.		Apoptosis , RAAS
T60507	Utreloxastat
	Utreloxastat is a compound used to study diseases including alpha-synucleinopathies, tauopathies, ALS, traumatic brain injury, and ischemic-reperfusion related injuries.
T5S1632	Barlerin	8-O-Acetylshanzhiside methyl ester,ND01	VEGFR , TNF , NF-κB , Akt , Caspase
	Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e...		VEGFR , TNF , NF-κB , Akt , Caspase
T21757	BRL 52537 hydrochloride		Opioid Receptor
	BRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury[1]. It is used for research into potential treatments for stroke and heart attack...		Opioid Receptor
T50100	3-hydroxy-3-phenylpentanamide		Others
	3-hydroxy-3-phenylpentanamide is a chiral compound belonging to the class of beta-hydroxyamides. In neurology, it has been shown to have neuroprotective effects against ischemic brain injury and cerebral hemorrhage. In p...		Others
T15463	(Rac)-HAMI 3379	HAMI 3379	Others
	HAMI 3379 is a potent and selective antagonist of the Cysteinyl leukotriene (CysLT2) receptor. HAMI 3379 has a protective effect on acute and subacute ischemic brain injury. It also attenuates microglia-related inflammat...		Others
T77995	NNZ 2591
	NNZ 2591, a synthetic analogue of cyclic glycine-proline (cGP), exhibits oral activity and the ability to cross the blood-brain barrier. This compound demonstrates neuroprotective properties following ischemic brain inju...
T73989	Tirilazad
	Tirilazad, a nonglucocorticoid 21-aminosteroid, serves to inhibit lipid peroxidation. It mitigates the effects of trauma-induced brain or spinal cord injury, as well as damage resulting from stroke, ischemia, and reperfu...
TN3323	Monomethyl lithospermate	Lithospermic acid monomethyl ester	Akt , PI3K
	Monomethyl lithospermate (Lithospermic acid monomethyl ester) has potential antiviral activity, alleviating ischemic stroke injury in vivo in middle cerebral artery occlusion mice by activating PI5K/Akt signaling and pro...		Akt , PI3K
T36722	Deltorphin II (trifluoroacetate salt)
	Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [3...